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learn more about integrative medicine doctor dr. dan monti, author & director of the marcus institute of integrative health in philadelphia.
meet christopher, who was treated at memorial sloan kettering for stomach cancer that spread to his brain.
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background cancer is the most prevalent cause of death globally, and radiotherapy is considered the standard of care for most solid tumors, including lung, breast, esophageal, and colorectal cancers and glioblastoma. resistance to radiation can lead to local treatment failure and even cancer recurrence. main body in this review, we have extensively discussed several crucial aspects that cause resistance of cancer to radiation therapy, including radiation-induced dna damage repair, cell cycle arrest, apoptosis escape, abundance of cancer stem cells, modification of cancer cells and their microenvironment, presence of exosomal and non-coding rna, metabolic reprogramming, and ferroptosis. we aim to focus on the molecular mechanisms of cancer radiotherapy resistance in relation to these aspects and to discuss possible targets to improve treatment outcomes. conclusions studying the molecular mechanisms responsible for radiotherapy resistance and its interactions with the tumor environment will help improve cancer responses to radiotherapy. our review provides a foundation to identify and overcome the obstacles to effective radiotherapy.
trio is a not-for-profit, full-service oncology cro that leverages a global network of investigators to accelerate the delivery of quality oncology trials.
richmond university medical center (rumc) provides health services to staten island, ny, including anesthesia, behavioral health, mental health, substance abuse, cardiology, community programs and support groups, diabetes, emergency services, endoscopy, epilepsy center, nursing services, obstetrics and gynecology, oncology (cancer), ophthalmology, orthopedic surgery, pain management, pastoral care and support, patient relations, pediatrics, radiology, rehabilitation, sleep center, stroke center, surgery, urology, world trade center medicalmonitoring program, wound care and more.
learn more about gresser, kira at instituteofliving.org
a cancer diagnosis can be extremely stressful and life-altering for patients. chronically high levels of stress can increase inflammation and affect the progression of the cancer. psychosocial interventions could reduce stress and address cancer ...
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faculty from the fitzpatrick college of nursing are teacher-scholars who seek opportunities to innovate, disseminate their research findings in top journal publications, and mentor students in the research process.
mary frances mcaleer, m.d., ph.d., department of cns - rad onc clinical, division of radiation oncology
it is imperative that nurses and other health care professionals not only recognize the disparities in preventive screenings but become part of the solution. early detection and cancer treatment must be accessible for those with disabilities, as it can help save lives.
as i reflect on the past three years of my life, if i were to sum things up in one word, it would be: grateful. incredibly grateful. my journey has been
research in neuroscience, natural treatments, and more dr. daniel a. monti’s extensive research experience has focused on neuroscience, brain effects of mind-body interventions, brain mechanisms of healing and recovery, and testing natural molecules for therapeutic efficacy in nervous system diseases and cancer. as both a clinical physician and researcher, he…
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lamia p. barakat, phd, is the director of psychosocial services and behavioral oncology research at children’s hospital of philadelphia. she holds the stephen and susan kelly endowed chair in behavioral oncology.
background this cross-sectional, nested cohort study assessed female sexual function index (fsfi) scores in postmenopausal women with breast cancer receiving primary chemotherapy. methods the fsfi questionnaire was administered to 24 postmenopausal women one month after diagnosis of breast cancer (post-diagnosis group) and one month after completion of the first cycle of primary anthracyclin-based chemotherapy (post-chemotherapy group). scores were compared to those of 24 healthy postmenopausal women seeking routine gynecological care (control group). all patients were sexually active at the time of enrollment. mean age was 57.29 ± 11.82 years in the breast cancer group and 52.58 ± 7.19 years in the control group. results scores in all domains of the fsfi instrument were significantly lower in the post-diagnosis group than in controls (−41.3%, p < 0.001). a further major reduction in fsfi scores was evident on completion of one cycle of primary chemotherapy (down 46.7% from post-diagnosis scores, p < 0.003), again in all domains. six patients (25%) ceased all sexual relations, in a significant change from baseline (p < 0.001). after one chemotherapy cycle, a further five patients ceased sexual activity, for a total of 11 (45.8%) participants – a borderline significant difference (p = 0.063). conclusion the present study shows that female sexual function as assessed by the fsfi declines significantly at two distinct points in time: upon diagnosis of breast cancer and after administration of systemic chemotherapy.
when five-year-old cj was diagnosed with rhabdomyosarcoma, his radiation oncologist made a plan to maximize the effectiveness and minimize the side effects of his treatment.
tami l. bach, m.d., ph.d., is board certified in both hematology and oncology. dr. bach graduated cum laude from villanova university with a major in biology.
hif1 and nfkb are two transcription factors very frequently activated in tumors and involved in tumor growth, progression and resistance to chemotherapy. i...
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meet dr. monti daniel a. monti, md, mba is founder and ceo of the marcus institute of integrative health. he is also the founding chair of the department of integrative medicine and nutritional sciences at sidney kimmel medical college, thomas jefferson university—the historic, first-ever department of integrative medicine at a…
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major philanthropic support has been fundamental to the growth and success of the marcus institute of integrative health.
about biomedicine and the philosophy of the zabrecky institute of biomedicine located in villanova, pa.
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